Quote from rmillay on Feb 9th, 2015, 8:46pm:I've had the R.H. skewer come loose on my 700. The trike felt sluggish, but I put it down to tired legs. I noticed it by chance, and retightening it gained me more speed. If you're used to your trike, pay attention to its feel. Now I check the skewers regularly.
On older Catrikes the axles are usually locked in place in the spindles, due to rust, so a rider isn't going to be stranded if a skewer happens to fall out. The hub shifts and the brake disk rubs on one or the other brake pads, if a skewer falls out or loosens, resulting in the sluggishness Bob mentions above.